Neurosciences

Overview

The Neuroscience area is consolidating its position as one of the largest clusters of research labs working on neurological diseases across Europe. Thirteen groups are currently part of this area, working closely with top clinicians at the hospital. The area encompasses different aspects related to neuroscience, such as neural development, neurodegeneration, neuroimmunology, neurological pain, mental health, neurosurgery or pediatric neurology.

There are groups also focused on cell signaling and apoptosis and translational bioinformatics.

Publications

183

total

815.974

impact factor

4.459

average impact factor

Director: Miguel Chillón Rodríguez

team

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We have demonstrated by gene therapy strategies that continue expression of secreted-Klotho protects against age-dependent memory deficits during aging (Molecular Psychiatry). To our knowledge, this is the first time gene therapy has been used to ameliorate cognitive decline in natural aging. Also, in collaboration with Dr. X. Montalban and C. Espejo (Cemcat) we have demonstrated the clinical and histopathological amelioration of Multiple Sclerosis symptoms by AAVs expressing soluble IL23R (Neurotherapeutics). During 2017, we have also been granted with 2 new grants (SmartMoney and TECNIO) and obtained 1 important research contract with the US company Klogene to analyze the effect of Klotho in Alzheimer. Also, in 2017 our technological platform (UPV) has produced more than 100 viral batches for costumers. Last, we have co-organized the 2nd National Adenonet meeting, and have presented 16 scientific communications (7 of them oral) in national and international congresses.

Neurosciences

Overview

Publications

Director: Miguel Chillón Rodríguez

Research Areas