Neurosciences

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Overview

The Neuroscience area is consolidating its position as one of the largest clusters of research labs working on neurological diseases across Europe. Thirteen groups are currently part of this area, working closely with top clinicians at the hospital. The area encompasses different aspects related to neuroscience, such as neural development, neurodegeneration, neuroimmunology, neurological pain, mental health, neurosurgery or pediatric neurology.

There are groups also focused on cell signaling and apoptosis and translational bioinformatics.

Publications

183
total
815.974
impact factor
4.459
average impact factor

Director: Ramon Martí Seves

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Research Areas

Our main achievements during 2017 can be summarized in three different areas:

  1. We demonstrated the long-term efficacy of our gene therapy strategy MNGIE in a preclinical model for the AAV vector (Torres-Torronteras et al, MHum Gen Ther 2018), similarly to that we had previously demonstrated for the lentiviral vector (Torres-Torronteras et al, Hum Gene Ther, 2016).
  2. We obtained Orphan drug designation for the use of thymidine and deoxycytidine for treatment of TK2 deficiency, and licensed to MODIS Therapeutics the patent covering this use.
  3. We obtained a knockin Gfm1 murine model for the study of the hepatoencephalopathy due to EFG1 deficiency, which is currently under study in our laboratory.

VHIR Annual Report 2017

© FIR-HUVH Fundació Institut de Recerca Hospital Universitari Vall d’Hebron 2017 | Developed by: ondeuev