Infectious Diseases

Overview

The aim of the seven groups of this area is to improve the outcomes of patients with infectious diseases. The Epidemiology and Public Health group is mainly focused on the epidemiology and prevention of healthcare acquired infections, transmissible infections and on the new preventive vaccines. The Infectious Diseases group focuses on improving the strategies of clinical problems observed in clinical practice. Microbiology studies mechanisms of resistance to antimicrobials, pathogenicity, taxonomy and epidemiology, and infectious diseases diagnostics.

The CRIPS group focuses on the most prevalent aspects of infections in the intensive care unit (ICU), while SODIR group works in the areas of shock, organ dysfunction and resuscitation.

There is also a group focused on infection in immunocompromised pediatric patients, and a group from the CIBBIM-Nanomedicine interested in the synthesis, characterization and applications of engineered inorganic nanoparticles in the field of medicine.

Publications

236

total

1,029.655

impact factor

4.363

average impact factor

Director: Ricard Ferrer Roca

team

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During 2017, SODIR has obtained the AGAUR accreditation as an emerging research group.

In collaboration with the Microbiology research group of VHIR, the sepsis research line has consolidated the Sepsis Bank as a support platform for biomedical research in sepsis. This line continues to work with special interest in the identification of biomarkers for the early diagnosis and stratification of patients with sepsis through transcriptomics, metabolomics and proteomics studies, applying systems biology techniques and big data analysis. It also has great interest in early microbiological identification of sepsis using molecular identification techniques that allow the optimization of antimicrobial treatment.

During the year 2017, SODIR has consolidated the Clinical Research Unit as the centralizing unit of all the clinical trials that are carried out in the group, providing a professional and excellent clinical research.

SODIR, through the line of research in lung transplantation, has started a study with competitive funding (Health Institute Carlos III) that aims to analyze the DNA of the donor and its relationship with the pulmonary inflammatory response. It is also important to highlight the studies carried out by the line of research in acute respiratory failure focused on the study of the mechanisms underlying the onset and progression of acute respiratory failure.

19

total

81^.125

impact factor

4^.270

average impact factor

SELECTED ARTICLES

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.
Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky JE, Sprung CL, Nunnally ME, Rochwerg B, Rubenfeld GD, Angus DC, Annane D, Beale RJ, Bellinghan GJ, Bernard GR, Chiche JD, Coopersmith C, De Backer DP, French CJ, Fujishima S, Gerlach H, Hidalgo JL, Hollenberg SM, Jones AE, Karnad DR, Kleinpell RM, Koh Y, Lisboa TC, Machado FR, Marini JJ, Marshall JC, Mazuski JE, McIntyre LA, McLean AS, Mehta S, Moreno RP, Myburgh J, Navalesi P, Nishida O, Osborn TM, Perner A, Plunkett CM, Ranieri M, Schorr CA, Seckel MA, Seymour CW, Shieh L, Shukri KA, Simpson SQ, Singer M, Thompson BT, Townsend SR, Van der Poll T, Vincent JL, Wiersinga WJ, Zimmerman JL, Dellinger RP.
Intensive Care Med. 2017; 43:304-37.
DOI: 10.1007/s00134-017-4683-6
IF 12.05
A multifaceted educational intervention shortened time to antibiotic administration in children with severe sepsis and septic shock: ABISS Edusepsis pediatric study.
Esteban E, Belda S, Garcia-Soler P, Rodriguez-Nunez A, Calvo C, Gil-Anton J, Bustinza A, Iglesias-Bouzas MI, Pujol-Jove M, deCarlos JC, Garcia-Iniguez JP, Perez-Iranzo A, Tellez C, Ortiz I, Perez R, Bonil V, Brio S, Concha A, Lopez JD, Murga V, Flores JC, Trujillo A, Felipe A, Abadesso C, Pino M, Leon J, Martinez MC, Gomez F, Perez-Montejano R, Tapia R, Jordan I, Ferrer R.
Intensive Care Med 2017; 43:1916-1918
DOI 10.1007/s00134-017-4721-4
IF 12.05
Hypoxemic patients with bilateral infiltrates treated with high-flow nasal cannula present a similar pattern of biomarkers of inflammation and injury to acute respiratory distress syndrome Patients.
García-de-Acilu M, Marin-Corral J, Vázquez A, Ruano L, Magret M, Ferrer R, Masclans JR, Roca O.
Crit Care Med. 2017; 45:1845-1853
DOI: 10.1097/CCM.0000000000002647
IF 7.05
PMID: 28806218
Epidemiology of sepsis in Catalonia: analysis of incidence and outcomes in a European setting.
Yebenes JC, Ruiz-Rodriguez JC, Ferrer R, Cleries M, Bosch A, Lorencio C, Rodriguez A, Nuvials X, Martin-Loeches I, Artigas, A.
Ann Intensive Care. 2017; 7:19.
DOI: 10.1186/s13613-017-0241-1
IF 3.656
High-flow nasal cannula to prevent postextubation respiratory failure in high-risk non-hypercapnic patients: a randomized multicenter.
Fernandez R, Subira C, Frutos-Vivar F, Rialp G, Laborda C, Masclans JR, Lesmes A, Panadero L, Hernandez G.
Ann Intensive Care 2017; 7: 47.
DOI: 10.1186/s13613-017-0270-9
IF 3.656
PMID: 28466461l

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