Core Facilities
LAB ANIMAL SERVICE
Animals Used in Research
15,981TOTAL
14,666MICE
1,315RATS
Annual Average of cages and individuals/week
2,795MICE
119RATS
Active Procedures per Species
77MICE
23RATS
Active producers per area and species
| Animal Species | Mice | Rat |
|---|---|---|
| Oncology | 15 | 1 |
| Vacular Biology and Metabolism (VAM) | 19 | 4 |
| Neurosciences | 15 | 4 |
| Infectious Diseases | 1 | 1 |
| Digestive and Liver Diseases | 7 | |
| Immunomediated Diseases and Innovative Therapies | 3 | |
| Research in Surgery | 1 | |
| Obstetrics, Pediatrics and Genetics | 1 | |
| VHIO | 24 | |
| HUVH | 1 | |
| Others | 3 | |
| TOTAL | 77 | 23 |
| Number of Procedures | 100 | |
Experimental Surgery Unit
| Animals used in Research | |
|---|---|
| Rabbits | 454 |
| Sheep | 17 |
| Pigs | 137 |
| TOTAL | 608 |
| Annual Average of Cages and Individuals / Week | |
|---|---|
| Rabbits | 20 |
| Sheep | 6 |
| Pigs | 6 |
| TOTAL | 32 |
| Active procedures per species | |
|---|---|
| Rabbits | 6 |
| Sheep | 2 |
| Pigs | 18 |
| Ex vivo procedures | 2 |
| TOTAL | 28 |
Active procedures per area and species
| Animal Species | Rabbit | Sheep | Pig |
|---|---|---|---|
| Oncology | 1 | ||
| Vacular Biology and Metabolism (VAM) | 3 | ||
| Neurosciences | 3 | ||
| Infectious Diseases | 1 | ||
| Research in Surgery | 1 | 1 | |
| Obstetrics, Pediatrics and Genetics | 1 | 1 | |
| HUVH | 4 | ||
| Others | 4 | 6 | |
| TOTAL | 6 | 2 | 18 |
| Number of Procedures | 26 | ||
Preclinical imaging plataform activity per group
| RESEARCH GROUPS | IVIS SPECTRUM | mCT | ||
|---|---|---|---|---|
| Acquiring Hours | Quantification and Analysis Hours | Acquired Studies | Quantification Analysis Hours | |
| Translational Research in Child and Adolescent Cancer | 20.5 | 6 | ||
| Functional Validation and Preclinical Research | 89 | 177 | 14 | |
| Musculoskeletal Tissue Engineering | 31 | |||
| Cell Signaling and Apoptosis | 2.5 | |||
| Liver Diseases | 9.5 | 6 | ||
| Neurovascular Diseases | 6 | |||
| VHIO | 636.25 | 78.25 | 1342 | 135 |
| Others | 15 | |||
| Total hours | 764 | 179 | 1550 | 164 |
BIOBANK
Number of new Biobank donations
3,453TOTAL
| Cardiology Bank | 251 |
|---|---|
| Fetal Tissue Bank | 3 |
| IMID | 445 |
| Immunology Bank | 177 |
| Gestational Pathologies Bank | 28 |
| Nephrology Bank | 137 |
| Neurological Tissue Bank | 2 |
| Pediatric Endocrinology Bank | – |
| Pulmonar Bank | 773 |
| Sepsis Bank | 819 |
| Tumor Bank | 818 |
Number of Projects which have asked for sample processing services
7CARDIOLOGY BANK
3IMMUNOLOGY BANK
3GESTATIONAL PATHOLOGIES BANK
5NEPFROLOGY BANK
2PULMONARY BANK
1SEPSIS BANK
3OTHERS
Number of Projects which have asked for samples (Material Transfer Service)
7CARDIOLOGY BANK
2FETAL TISSUE BANK
4IMID
1IMMUNOLOGY BANK
2NEPFROLOGY BANK
2PULMONARY BANK
6SEPSIS BANK
6TUMOR BANK
Number of publications which have used biobank sample collections
1FETAL TISSUE BANK
4IMID
21TUMOR BANK
UAT (High Technology Unit)
User groups
36VHIR
3ALLIANCES (VHIO, CIBER, UAB)EXTERNS (CIBER, UAB)
6EXTERNS (OPIS)
0EXTERNS (PRIVATE)
Services performed
1,429MOLECULAR DIAGNOSIS
5,485GENOMICS
2,777MICROSCOPY
1,429CYTOMICS
1,158METABOLOMICS
Courses organised
| Title | Category |
|---|---|
| Basic course in microscopy and data analysis | Microscopy Platform |
| Omic Data Integration | Molecular Diagnosis Platform |
| Real-time Microscopy Demo | Tecnologic external seminar (theory&practise) |
| Measuring metabolic engines and fuels | Tecnologic external seminar (theory&practise) |
| New technologies in Genomics and Proteomics. Digital molecular quantification. | Tecnologic external seminar |
| Escolab students’ visits | UAT staff participation |
| VHIR’s Master | UAT staff participation |
Current agreements with external services providers
| NAME | SERVICES PROVIDED |
|---|---|
| Centro de Investigaciones Biomédicas Alberto Sols | Human cell line authentication |
| Centre for Genomic Regulation (CRG) | Institutional agreement to improve core-facilities sharing |
| Universitat Autònoma de Barcelona (UAB) | Institutional agreement to improve core-facilities sharing |
| National Centre for Genomic Analysis (CNAG) | Next Generation Sequencing |
| Macrogen | Sanger Sequencing |
| OWL | Lipidomics |
| Anaxomics | System Biology Solutions |
|
Public Private |
|
New internal services
| PLATFORM | SERVICE |
|---|---|
| Microscopy | Study of fast dynamics of calcium fluxes in eosinophils degranulation |
| Molecular Diagnosis | Clariom D arrays processing |
| Molecular Diagnosis | miRNA arrays from acellular samples |
| Metabolomics | Bioanalytical procedures for the determination of different drugs in nanoparticle matrices |
USIC (Clinical Research Support Unit)
USIC-Healthcare Platform
| % clinical trials USIC-Healthcare Area/ active clinical trials in HUVH | 23,0% |
|---|---|
| % of the use of healthcare spaces | 60,5% |
| Request of studies for medical consultation | 177 |
| Request of studies for day hospital | 21 |
| Request of studies for support of research nurse | 143 |
| No. of visits | 6,100 |
| No. intravenous treatments | 157 |
| No. principal investigators | 50 |
| Services/Units of HUVH | 26 |
| Clinical trials/studies active during 2017 | 202 |
| Petitions of public funded studies | 31 |
| Petitions of private funded studies | 171 |
| No. spaces used for monitoring/auditories/center selection visits, start-up and close-out visits | 482 |
UEB (Statistic and Bioinformatics)
UEB services by type
| TOTAL (€) | TOTAL (hours) | |
|---|---|---|
| Teaching activities (Courses & Personalized) | 8,113.0 | 312.0 |
| Advanced Data Analysis | ||
| High Throughput Data Analysis (Bioinformatics) | 38,424.0 | 1,478.0 |
| Data Analysis for Clinical Research (Biostatistics) | 33,227.0 | 1,278.0 |
| Statistical & methodological consultancy services | 425.0 | |
| Scientific results communication | ||
| Database & applications development | 9,545.0 | 367.0 |
| Report writing and Documentation development writings | ||
| Booking of UEB resources | 868.0 | 133.0 |
| TOTAL | 90,177.0 | 3,992.7 |
UEB results by user type
| TOTAL (€) | TOTAL (hours) | |
|---|---|---|
| Internal | 79,072.0 | 3,008.0 |
| UAB | 6,468.0 | 208.3 |
| OPIs | 3,662.0 | 112.7 |
| External-Private | 975.0 | 25.0 |
| Support Units | 95.0 | |
| TOTAL | 90,177.0 | 3,448.9 |
ARO (Academic Research Organization)
Services we have worked with
| Oncology | 8 |
|---|---|
| Digestive System | 4 |
| Rheumatology | 2 |
| Anesthesia | 1 |
| Cardiology | 4 |
| Neurology | 2 |
| Infectious Diseases | 5 |
| Hematology | 3 |
| Hepatology | 5 |
| Surgery | 2 |
| Allergology | 1 |
| Ginecology | 3 |
| Transplant | 3 |
| Rehabilitation | 2 |
| Endocrinology | 1 |
| Dermatology | 1 |
| Traumatology | 1 |
| Radiology | 1 |
| Nephrology | 1 |
| Pharmacy | 1 |
| Inmunology | 1 |
| Peadiatric Pneumology | 1 |
| TOTAL | 53 |
Phases of the studies
Development area
36NATIONALS
17INTERNATIONALS
Centers participating
20UNICENTRIC
33MULTICENTRIC
Promoter
6 | 11.32%MEDICAL SOCIETY
23 | 43.40%VHIR
3 | 5.66%PHARMACEUTICAL LABORATORIES
17 | 32.08%HOSPITAL
4 | 7.55%UNIVERSITY
Clinical studies managed through networks
| N | % | |
|---|---|---|
| SCReN | 13 | 24,53 |
| ECRIN | 4 | 7,55 |
| Out of networks | 36 | 67,92 |
